The Belle of the Ball: PD-1 as a Hot New Target

5 Jun 2012, by Gordon Gochenauer

These studies demonstrate the potential of targeting the PD-1/PD-L1 checkpoint as a therapeutic strategy. These molecules appear to be very well tolerated and have efficacy in many advanced tumor types. Many questions remain unanswered about this novel approach to targeting cancer including: is efficacy limited to tumors that express PD-L1? ASCO 2012 MORE